Last update
4/9/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.7
USERS' SCORE
Good
Based on 13 Reviews
8
Supplement Facts
Serving Size: 1 Fish Softgel
Amount Per Serving
%DV
Calories
15
Total Fat
1.5 g
2%**
Cholesterol
<5 mg
1%
Vitamin D3 (as Cholecalciferol) (from Lanolin)
25 mcg (1,000 IU)
125%
Fish Oil Concentrate
1.2 g (1,200 mg)
†
Omega-3 Fatty Acids:
Eicosapentaenoic Acid (EPA)
600 mg
†
Docosahexaenoic Acid (DHA)
300 mg
†
Top Medical Research Studies
8
Eicosapentaenoic acid shows potential
We assessed how eicosapentaenoic acid, an essential fatty acid, impacts chronic fatigue syndrome (CFS). A group of CFS patients took a specific supplement rich in this fatty acid. Remarkably, every participant reported symptom improvement within eight to twelve weeks.
These findings align with other research that shows the positive effects of eicosapentaenoic acid, hinting that it could be a promising treatment option for some individuals living with CFS.
These findings align with other research that shows the positive effects of eicosapentaenoic acid, hinting that it could be a promising treatment option for some individuals living with CFS.
Read More
4
We explored the connection between omega-3 fatty acids and chronic fatigue syndrome (CFS) by examining serum levels in 22 CFS patients and 12 healthy controls. Our findings revealed that CFS patients had lower omega-3 levels compared to controls, along with higher omega-6 levels.
Interestingly, we observed that these imbalances correlated with the severity of fatigue and other symptoms. Additionally, lower omega-3 availability linked to poorer immune function was noted. These results suggest that omega-3 supplementation could be beneficial for those suffering from CFS.
Interestingly, we observed that these imbalances correlated with the severity of fatigue and other symptoms. Additionally, lower omega-3 availability linked to poorer immune function was noted. These results suggest that omega-3 supplementation could be beneficial for those suffering from CFS.
Read More
8
We investigated the effects of a daily eicosapentaenoic acid (EPA)-rich supplement on a woman suffering from chronic fatigue syndrome for six years. After 16 weeks of treatment, she experienced significant symptom relief starting within the first 6-8 weeks.
Additionally, brain scans revealed a notable reduction in the size of her lateral ventricles, which is promising. This early-stage observation suggests that EPA supplementation might offer benefits for individuals dealing with chronic fatigue syndrome.
Additionally, brain scans revealed a notable reduction in the size of her lateral ventricles, which is promising. This early-stage observation suggests that EPA supplementation might offer benefits for individuals dealing with chronic fatigue syndrome.
Read More
Most Useful Reviews
9
Increased energy
I ordered lecithin for myself and my mother, spending time selecting a good remedy for bile. This product has been very helpful; I began to feel well, energy emerged, fatigue diminished, and I truly appreciated the benefits of lecithin. My mother also became lively and her memory improved.
Read More
9
Increased energy levels
I took a course of 90 tablets, two each day. Over a month and a half, I noticed a significant boost in energy, and I forgot about feelings of drowsiness and fatigue during the day. I've ordered a larger quantity again.
Read More
9
Improved well-being
This omega is perfect! It eliminated my state of deficiency. My heart troubles have ceased, and my skin condition improved significantly. I no longer experience morning fatigue. I recommend taking it for life, similar to Vitamin D3.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.7
- All Researches
8
We investigated the effects of a daily eicosapentaenoic acid (EPA)-rich supplement on a woman suffering from chronic fatigue syndrome for six years. After 16 weeks of treatment, she experienced significant symptom relief starting within the first 6-8 weeks.
Additionally, brain scans revealed a notable reduction in the size of her lateral ventricles, which is promising. This early-stage observation suggests that EPA supplementation might offer benefits for individuals dealing with chronic fatigue syndrome.
Additionally, brain scans revealed a notable reduction in the size of her lateral ventricles, which is promising. This early-stage observation suggests that EPA supplementation might offer benefits for individuals dealing with chronic fatigue syndrome.
Read More
8
Eicosapentaenoic acid shows potential
We assessed how eicosapentaenoic acid, an essential fatty acid, impacts chronic fatigue syndrome (CFS). A group of CFS patients took a specific supplement rich in this fatty acid. Remarkably, every participant reported symptom improvement within eight to twelve weeks.
These findings align with other research that shows the positive effects of eicosapentaenoic acid, hinting that it could be a promising treatment option for some individuals living with CFS.
These findings align with other research that shows the positive effects of eicosapentaenoic acid, hinting that it could be a promising treatment option for some individuals living with CFS.
Read More
4
We explored the connection between omega-3 fatty acids and chronic fatigue syndrome (CFS) by examining serum levels in 22 CFS patients and 12 healthy controls. Our findings revealed that CFS patients had lower omega-3 levels compared to controls, along with higher omega-6 levels.
Interestingly, we observed that these imbalances correlated with the severity of fatigue and other symptoms. Additionally, lower omega-3 availability linked to poorer immune function was noted. These results suggest that omega-3 supplementation could be beneficial for those suffering from CFS.
Interestingly, we observed that these imbalances correlated with the severity of fatigue and other symptoms. Additionally, lower omega-3 availability linked to poorer immune function was noted. These results suggest that omega-3 supplementation could be beneficial for those suffering from CFS.
Read More
User Reviews
USERS' SCORE
Good
Based on 13 Reviews
8
- All Reviews
- Positive Reviews
- Negative Reviews
9
Increased energy
I ordered lecithin for myself and my mother, spending time selecting a good remedy for bile. This product has been very helpful; I began to feel well, energy emerged, fatigue diminished, and I truly appreciated the benefits of lecithin. My mother also became lively and her memory improved.
Read More
9
Increased energy levels
I took a course of 90 tablets, two each day. Over a month and a half, I noticed a significant boost in energy, and I forgot about feelings of drowsiness and fatigue during the day. I've ordered a larger quantity again.
Read More
9
Improved well-being
This omega is perfect! It eliminated my state of deficiency. My heart troubles have ceased, and my skin condition improved significantly. I no longer experience morning fatigue. I recommend taking it for life, similar to Vitamin D3.
Read More
9
Vitamin D boost
These vitamins resolve vitamin D3 deficiency alongside omega 3. After taking them orally for two months, my levels returned to normal, chronic fatigue vanished, and my sleep improved. Highly recommend.
Read More
8
Effective supplement recommendation
I highly recommend it! After my latest examination, the doctor advised supplements and suggested the iHerb website. I ordered for the first time through friends. The results proved effective. Winter in Siberia is tough, with no sun and constant fatigue. I took the complex in the autumn, and after a three-month break, I'm currently taking omega-3 D and other supplements. I feel fantastic; my apathy has vanished, and I’m waiting for spring with a great mood. Thanks to iHerb for excellent vitamins and prices.
Read More
Frequently Asked Questions
9
Increased energy levels
I took a course of 90 tablets, two each day. Over a month and a half, I noticed a significant boost in energy, and I forgot about feelings of drowsiness and fatigue during the day. I've ordered a larger quantity again.
7.5
Mood enhancement observed
The Ultra Omega-3 combined with Vitamin D is an excellent health boost. After taking it, I noticed an improvement in my mood, reduced fatigue, and enhanced skin condition. I recommend it for supporting the cardiovascular system and overall well-being.
4
We explored the connection between omega-3 fatty acids and chronic fatigue syndrome (CFS) by examining serum levels in 22 CFS patients and 12 healthy controls. Our findings revealed that CFS patients had lower omega-3 levels compared to controls, along with higher omega-6 levels.
Interestingly, we observed that these imbalances correlated with the severity of fatigue and other symptoms. Additionally, lower omega-3 availability linked to poorer immune function was noted. These results suggest that omega-3 supplementation could be beneficial for those suffering from CFS.
Interestingly, we observed that these imbalances correlated with the severity of fatigue and other symptoms. Additionally, lower omega-3 availability linked to poorer immune function was noted. These results suggest that omega-3 supplementation could be beneficial for those suffering from CFS.
8
We investigated the effects of a daily eicosapentaenoic acid (EPA)-rich supplement on a woman suffering from chronic fatigue syndrome for six years. After 16 weeks of treatment, she experienced significant symptom relief starting within the first 6-8 weeks.
Additionally, brain scans revealed a notable reduction in the size of her lateral ventricles, which is promising. This early-stage observation suggests that EPA supplementation might offer benefits for individuals dealing with chronic fatigue syndrome.
Additionally, brain scans revealed a notable reduction in the size of her lateral ventricles, which is promising. This early-stage observation suggests that EPA supplementation might offer benefits for individuals dealing with chronic fatigue syndrome.
8
Eicosapentaenoic acid shows potential
We assessed how eicosapentaenoic acid, an essential fatty acid, impacts chronic fatigue syndrome (CFS). A group of CFS patients took a specific supplement rich in this fatty acid. Remarkably, every participant reported symptom improvement within eight to twelve weeks.
These findings align with other research that shows the positive effects of eicosapentaenoic acid, hinting that it could be a promising treatment option for some individuals living with CFS.
These findings align with other research that shows the positive effects of eicosapentaenoic acid, hinting that it could be a promising treatment option for some individuals living with CFS.
References
- Maes M, Mihaylova I, Leunis JC. In chronic fatigue syndrome, the decreased levels of omega-3 poly-unsaturated fatty acids are related to lowered serum zinc and defects in T cell activation. Neuro Endocrinol Lett. 2005;26:745. PubMed
- Puri BK, Holmes J, Hamilton G. Eicosapentaenoic acid-rich essential fatty acid supplementation in chronic fatigue syndrome associated with symptom remission and structural brain changes. Int J Clin Pract. 2004;58:297. PubMed
- Puri BK. The use of eicosapentaenoic acid in the treatment of chronic fatigue syndrome. Prostaglandins Leukot Essent Fatty Acids. 2004;70:399. PubMed
Data last updated:
